calling all fs experts

Hello,

i have a question for fs wizards.

suppose i can persuade modern spinning disk to do "large" reads (say
512K to 1M) at a time. also, suppose file system on such modern
spinning drive is used to store large files (tens to hundreds of
megabytes). is there any way i can tweak the file system parameters
(block size, layout, etc) to help it to get as close to "disk's
sequential read rate" as possible. I understand that i will not be
able to get 100MB/sec single client sequential read rate, but, can i
get it into sustained 40-50MB/sec rate? also, can i reduce performance
impact caused by "small reads" such as directory access etc.

thanks,
max